| 1． |
Three-dimensional Structure of Guanylyl Cyclase Activating Protein-2, a Calcium- sensitive Modulator of Photoreceptor Guanylyl Cyclases, James B. Ames, Alexander M. Dizhoor, Mitsuhiko Ikura, Krzysztof Palczewski, and Lubert Stryer, The Journal of Biological Chemistry, Vol. 274, No. 27, July (1999) 19329-19337 |
| 2． |
A Method for Global Analysis of Complex Proteomes Using Sample Prefractionation by Solution Isoelectrofocusing Prior to Two-Dimensional Electrophoresis, Xun Zuo and David W. Speicher, Analytical Biochemistry, Vol. 284, No. 2, September (2000) 266-278 |
| 3． |
Development of a High Throughput Equilibrium Dialysis Method, Ilona Kariv, Hong Cao, Kevin R. Oldenburg, Journal of Pharmaceutical Sciences, Vol. 90, No. 5, May (2001) 580-587 |
| 4． |
Structural features of a zinc binding site in the superantigen streptococcal pyrogenic exotoxin A (SpeA 1): Implications for MHC class II recognition, Matthew Baker, Delia M. Gutman, Anastassios C. Papageorgiou, Carleen M. Collins, and K. Ravi Acharya, Protein Science, June (2001), 10: 1268-1273 |
| 5． |
Differential ATP Binding and Intrinsic ATP Hydrolysis by Amino-terminal Domains of the Yeast Mlh1 and Pms1 Proteins, Mark C. Hall, Polina V. Shcherbakova, and Thomas A. Kunkel, The Journal of Biological Chemistry, Vol. 277, No. 5, February (2002) 3673-3679 |
| 6． |
Molecular Basis of the Specific Subcellular Localization of the C2-like Domain of 5-Lipoxygenase, Shilpa Kulkarni, Sudipto Das, Colin D. Funk, Diana Murray, and Wonhwa Cho, The Journal of Biological Chemistry, Vol. 277, No. 15, April (2002) 13167- 13174 |
| 7． |
Modulating Acetyl-CoA Binding in the GCN5 Family of Histone Acetyltransferases, Michael R. Langer, Christopher J. Fry, Craig L. Peterson, and John M. Denu, The Journal of Biological Chemistry, Vol. 277, No.30, July (2002) 27337-27344 |
| 8． |
Lateral Sequestration of Phosphatidylinositol 4,5-Bisphosphate by the Basic Effector Domain of Myristoylated Alanine-rich C Kinase Substrate Is Due to Nonspecific Electrostatic Interactions, Jiyao Wang, Alok Gambhir, Gyöngyi Hangyás-Mihályné, Diana Murray, Urszula Golebiewska, and Stuart McLaughlin, The Journal of Biological Chemistry, Vol. 277, No.37, September (2002) 34401-34412 |
| 9． |
Determination of Plasma Protein Binding in Support of Early ADME Drug Discovery Efforts by LC/MS/MS, John P. Walsh, Reginald O. Angeles, Kelly M. Jenkins, Robyn A. Rourick, Pittsburgh Conference March (2003) Poster |
| 10． |
Riboswitches Control Fundamental Biochemical Pathways in Bacillus subtilis and Other Bacteria, Maumita Mandal, Benjamin Boese, Jeffrey E. Barrick, Wade C. Winkler, and Ronald R. Breaker, Cell, Vol. 113, May (2003) 577-586 |
| 11． |
An mRNA structure that controls gene expression by binding S-adenosylmethionine, Wade C Winkler, Ali Nahvi, Narasimhan Sudarsan, Jeffrey E Barrick, and Ronald R Breaker, Nature Structural Biology, Vol. 10, No. 9, September (2003) 701-707 |
| 12． |
Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes, Ali Nahvi, Jeffrey E. Barrick, and Ronald R. Breaker, Nucleic Acids Research, Vol. 32, No. 1, January (2004) 143-150 |
| 13． |
Simultaneous determination of glipizide and rosiglitazone unbound drug concentrations in plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry, Zhongping John Lin, Daksha Desai-Krieger, Linyee Shum, Journal of Chromatography B, 801 (2004) 265-272 |
| 14． |
Distinct roles for ATP binding and hydrolysis at individual subunits of an archaeal clamp loader, Anja Seybert and Dale B Wigley, The EMBO Journal, Vol. 23, No.6, March (2004) 1360-1371 |
| 15． |
Determination of fraction unbound docetaxel using microequilibrium dialysis, Milin R.
Acharya, Sharyn D. Baker, Jaap Verweij, William D. Figg, and Alex Sparreboom, Analytical Biochemistry 331, May (2004) 192-194 |
| 16． |
Binding of gefitinib (ZD1839) to human plasma proteins: in vitro and clinical pharmacokinetic (PK) studies, Jing Li, Julie Brahmer, Wells Messersmith, Manuel
Hidalgo, and Sharyn D. Baker, 16th EORTC-NCI-AACR Meeting (2004) Geneva |
| 17． |
Relationship of systemic exposure to unbound docetaxel and neutropenia, Sharyn D.
Baker, Jing Li, Albert J. ten Tije, William D. Figg, Wilfried Graveland, Jaap Verweij,
and Alex Sparreboom, Clinical Pharmacology & Therapeutics, 77(1), January (2005) 43-53 |
| 18． |
創薬における探索薬物動態スクリーニング(I) -幅広い物性を有する化合物のための吸収評価系の確立- 小村 弘、河原亥一郎、茂本友貴枝、松田健一、阿野理恵子、村山洋子、森脇俊哉、吉田長弘、薬学雑誌 125 (1) 121-130 (2005) |
| 19． |
創薬における探索薬物動態スクリーニング(II) –代謝スクリーニングにおけるin vitroとin vivoの相関性の検討- 小村 弘、松田健一、茂本友貴枝、河原亥一郎、阿野理恵子、村山
洋子、森脇俊哉、吉田長弘、薬学雑誌 125 (1) 131-139 (2005) |
| 20． |
Kringle 5 of Human Plasminogen Induces Apoptosis of Endothelial and Tumor Cells through Surface-Expressed Glucose-Regulated Protein 78, Don J. Davidson, Catherine Haskell, Sandy Majest, Abdullah Kherzai, David A. Egan, Karl A. Walter, Andrew Schneider, Earl F. Gubbins, Larry Solomon, Zhebo Chen, Rick Lesniewski, and Jack Henkin, Cancer Res 65: (11), June (2005) 4663-4672 |
| 21． |
Automatable Formats of Higher Throughput ADMET Profiling for Drug Discovery Support, Paul V. Kaplita, Hanbo Hu, Lisa Liu, Thomas M. Farrell, Heather Grbic, and Denice M. Spero, JALA (Journal of the Association for Laboratory Automation) 10, June (2005) 140-148 |
| 22． |
Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha- proteobacteria, Keith A Corbino, Jeffrey E Barrick, Jinsoo Lim, Rüdiger Welz, Brian J Tucker, Izabela Puskarz, Maumita Mandal, Noam D Rudnick, and Ronald R Breaker, Genome Biology, Vol. 6, No. 8, Article R70 (2005) R70.1-R70.10 |
| 23． |
Modification of the Structure and Function of Fibrillin-1 by Homocysteine Suggests a Potential Pathogenetic Mechanism in Homocystinuria, Dirk Hubmacher, Kerstin Tiedemann, Rainer Bartels, Jürgen Brinckmann, Tillman Vollbrandt, Boris Bätge, Holger Notbohm, and Dieter P. Reinhardt, The Journal of Biological Chemistry, Vol. 280, No. 41, October (2005) 34946-34955 |
| 24． |
Interspecies differences in plasma protein binding of MS-275, a novel histone deacetylase inhibitor, Milin R. Acharya, Alex Sparreboom, Edward A. Sausville, Barbara A. Conley, James H. Doroshow, Jürgen Venitz, and William D. Figg, Cancer Chemother Pharmacol 57, February (2006) 275-281 |
| 25． |
Small Molecules That Enhance the Catalytic Efficiency of HLA-DM1, Melissa J. Nicholson, Babak Moradi, Nilufer P. Seth, Xuechao Xing, Gregory D. Cuny, Ross L. Stein, and Kai W. Wucherpfennig, The Journal of Immunology, 176, April (2006) 4208-4220 |
| 26． |
Quantitative LC-MS/MS Analysis of Endogenous Biomarkers for Clinical Diagnosis in Endocrinology, Mary K Morr, Andrew D Wagner, Milan Patel, Russell P Grant, ASMS May (2006) Poster |